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武汉168飞艇计划生物科技有限公司
热搜词：燕窝酸，不饱和脂肪酸，神经酰胺，花青素，黄酮，皂苷
Wuhan Chemstan Biotechnology Co., Ltd.
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产品名称：
Research Grade Necitumumab ( 奈妥木单抗 )
NO.
003
货号：
CSD00193
中文名称
奈妥木单抗
英文名词
Research Grade Necitumumab
CAS号
906805-06-9
产品货号：
CSD00193
货期：
现货
价格与订购：
2480.00
数量：
-
+
库存：
100
产品信息
如何订购
货号（Catalog No.）icon
CSD00193
通用名INNicon
Necitumumab
纯度(Purityicon
>95%
浓度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
内毒素(Endotoxin level)icon
Please contact with the lab for this information.
产品描述(Description)icon
Necitumumab is an intravenously administered recombinant monoclonal IgG1 antibody used in the treatment of non-small cell lung cancer (NSCLC) as an EGFR antagonist. It functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands, a process that is involved in cell proliferation, metastasis, angiogenesis, and malignant progression. Binding of necitumumab to EGFR induces receptor internalization and degradation, thereby preventing further activation of EGFR which is beneficial in NSCLC as many patients have increased protein expression of EGFR. Necitumumab is approved for use in combination with cisplatin and gemcitabine as a first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC).
别名(Alternative names)icon
11F8,IMC-11F8,LY3012211
靶点;物种(Specificity target name;species)icon
EGFR/ERBB1 [Homo sapiens]
种类(Species)icon
Homo sapiens
受体鉴定(Receptor identification)icon
IgG1-kappa
CASicon
906805-06-9
存储条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
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Research Grade Adalimumab ( 阿达木单抗 )
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