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地 址:武汉市东湖新技术开发区高新大道666号,武汉
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产品名称:
Research Grade Siltuximab ( 塞妥昔单抗 )
NO.
004
货号:
CSD00196
中文名称
塞妥昔单抗
英文名词
Research Grade Siltuximab
CAS号
541502-14-1
产品货号:
CSD00196
货期:
现货
价格与订购:
2480.00
数量:
-
+
库存:
100
产品信息
如何订购
货号(Catalog No.)icon
CSD00196
通用名INNicon
Siltuximab
纯度(Purity)icon
>95%
浓度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
内毒素(Endotoxin level)icon
Please contact with the lab for this information.
产品描述(Description)icon
Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology. Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). Its use is indicated for the treatment of adult patients with multicentric Castleman's disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. MCD is a rare blood disorder caused by dysregulated IL-6 production, proliferation of lymphocytes, and subsequent enlargement of the lymph nodes. It is administered as a 1 hour intravenous infusion every 3 weeks.
别名(Alternative names)icon
CLLB8,CNTO 328
靶点;物种(Specificity target name;species)icon
IL6[Homo sapiens]
种类(Species)icon
Chimeric
受体鉴定(Receptor identification)icon
IgG1-kappa
分子量(MV)icon
145000.00 Da
CASicon
541502-14-1
存储条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
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Research Grade Necitumumab ( 奈妥木单抗 )
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