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武汉168飞艇计划生物科技有限公司
热搜词：燕窝酸，不饱和脂肪酸，神经酰胺，花青素，黄酮，皂苷
Wuhan Chemstan Biotechnology Co., Ltd.
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产品名称：
Research Grade Sarilumab
NO.
009
货号：
CSD00271
中文名称
Research Grade Sarilumab
英文名词
Research Grade Sarilumab
CAS号
1189541-98-7
产品货号：
CSD00271
货期：
现货
价格与订购：
2480.00
数量：
-
+
库存：
100
产品信息
如何订购
货号（Catalog No.）icon
CSD00271
通用名INNicon
Sarilumab
纯度(Purityicon
>95%
浓度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
内毒素(Endotoxin level)icon
Please contact with the lab for this information.
产品描述(Description)icon
Sarilumab is a fully human anti-IL-6R monoclonal IgG1 antibody that binds to both membrane bound and soluble interleukin 6 (IL-6) receptor forms, thus blocking the cis- and trans-inflammatory signalling cascades of IL-6 1. Sarilumab was developped by Sanofi and Regeneron Pharmaceuticals, Inc; it was US FDA-approved in May 2017 and followed by EU approval in June 2017 for the treatment of moderate to severe Rheumatoid Arthritis (RA) in combination with methotrexate 4. RA is a chronic inflammatory disease characterized by polyarthritis and its treatment has been challenged by the different response in every patient 3. Subcutaneous administration of Sarilumab has been shown to decrease acute-phase reactant levels and improve in clinical RA symptoms 2.
别名(Alternative names)icon
REGN88,SAR153191
靶点;物种(Specificity target name;species)icon
EGFR/ERBB1 [Homo sapiens]
种类(Species)icon
Homo sapiens
受体鉴定(Receptor identification)icon
IgG1-kappa
分子量(MV)icon
150000.0 Da (143900 Da in absence of N-glycosylation in heavy chains (Asn296) )
CASicon
1189541-98-7
存储条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
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