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热搜词：燕窝酸，不饱和脂肪酸，神经酰胺，花青素，黄酮，皂苷
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产品名称：
Recombinant SARS-CoV-2(2019-nCoV) S +E +M protein
NO.
016
货号：
CSEP02447COV
中文名称
新冠相关蛋白
英文名词
Recombinant SARS-CoV-2(2019-nCoV) S +E +M protein
CAS号
/
产品货号：
CSEP02447COV
货期：
现货
价格与订购：
2880.00
数量：
-
+
库存：
100
产品信息
如何订购
产品名称（Product name）icon
Recombinant SARS-CoV-2(2019-nCoV) S +E +M protein
货号（Catalog#）icon
CSEP02447COV
描述（description）icon
Recombinant SARS-CoV-2 S&M&E fusion is produced by E.coli expression system and the target gene encoding Arg319-Phe541&Arg38-Val75&Arg101-Gln222 is expressed with C-His Tag
表达系统（Expression system）icon
E.coli
种属（Species）icon
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Accession #
Accession #
别名（Alternative names)icon
Spike glycoprotein;Envelope small membrane protein, E protein;Membrane protein
预测分子量（Predicted Molecular Mass）icon
44.7kDa
纯度（Purity）icon
>90% as determined by SDS-PAGE
内毒素（Endotoxin level）icon
Please contact with the lab for this information
制剂（Formulation）icon
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
运输方式（Shipping）
icon
In general, proteins are shipped out with blue ice unless customers require otherwise.
稳定性&储存（Stability &Storage）icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶（Reconstitution）
Please refer to the instraction in the hard copy of COA.
应用（Application）icon
Immunogen
背景（Background）
icon
icon
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Note
iconicon
iconicon
For research use only .
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Recombinant SARS-CoV-2(2019-nCoV) NSP10
Recombinant SARS-CoV-2(2019-nCoV) S1 Protein
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